TY - JOUR AU - Cafini, Fabio AU - Yuste, Jose AU - Giménez, María José AU - Sevillano Fernández, David AU - Aguilar, Lorenzo AU - Alou Cervera, Luis AU - Ramos Sevillano, Elisa AU - Torrico, Martha AU - González Hidalgo, Natalia AU - García, Ernesto AU - Coronel, Pilar AU - Prieto Prieto, José AU - Michael Otto PY - 2010 DO - 10.1371/journal.pone.0012041 SN - 1932-6203 UR - https://hdl.handle.net/20.500.14352/106738 T2 - PLoS One AB - Background: Specific antibodies are likely to be present before S. pneumoniae infection. We explored cefditoren (CDN) total and free values of serum concentrations exceeding the MIC (t>MIC) related to efficacy in a mice sepsis model, and the effect of... LA - eng M2 - e12041 PB - PLOS TI - Enhanced In Vivo Activity of Cefditoren in Pre-Immunized Mice against Penicillin-Resistant S. pneumoniae (Serotypes 6B, 19F and 23F) in a Sepsis Model TY - journal article VL - 5 ER -