%0 Journal Article %A Barambio, J. %A León Bretscher, Ana %A Ramírez Bescós, María %A Soto García, Paula %A Gadea Uría, Paloma %A Laloumet Garcimartín, Teresa %A Viejo Martínez, Elena %A Acedo Fernández De Pedro, Felipe %A Ortega Domene, Patricia %A Ruiz de la Hermosa, Alicia %A De Fuenmayor Valera, María Luisa %A Paseiro Crespo, Gloria Marta %T Infuence of seton confguration, thickness, and laxity on patient comfort in chronic perianal fistula: a prospective comparative study %D 2025 %U https://hdl.handle.net/20.500.14352/124346 %X PurposeTo determine how seton configuration, thickness, and laxity influence patient comfort and clinical outcomes in the management of chronic perianal fistulas.MethodsA prospective single-center study was conducted involving 33 patients (53 setons). Both intraindividual paired (n = 20) and independent group analyses (n = 13) were performed. Setons were categorized by configuration (O-shaped vs. V-shaped), thickness (1.5 mm vs. 2.5 mm), and laxity (≤ 2 cm vs. > 2 cm from the anal verge). Patient-reported outcomes were assessed using structured questionnaires evaluating sitting discomfort, discharge, sexual impact, and fecal incontinence.ResultsO-shaped setons caused significantly less sitting discomfort than V-shaped ones (50.0% vs. 80.0%, p = 0.021). Excess laxity (> 2 cm) was associated with increased discharge (86.4% vs. 51.6%, p = 0.008), sexual impact (42.1% vs. 10.3%, p = 0.016), and fecal incontinence (66.7% vs. 10.0%, p = 0.041). Thicker setons (2.5 mm) showed a non-significant trend toward more pain (42.9% vs. 17.9%, p = 0.080).ConclusionSeton configuration and laxity significantly affect patient comfort. O-shaped setons and shorter laxity (≤ 2 cm) are preferable for reducing discomfort. These findings support evidence-based seton selection, although larger multicenter studies are needed to confirm these results. %~