RT Journal Article T1 Fatty acids and minor functional compounds of hemp (Cannabis sativa L.) seeds and other Cannabaceae species A1 Alonso Esteban, José Ignacio A1 González Fernández, María José A1 Fabrikov, Dmitri A1 Sánchez Mata, María De Cortes A1 Torija Isasa, Esperanza A1 Guil Guerrero, José Luis AB Nowadays, hemp (Cannabis sativa) seeds are receiving increased attention because of their high nutritional value. Among other nutrients, they contain a PUFA- and bioactive compounds-rich oil. Accordingly, this work was focused to establish the fatty acids (FA) content, the regiospecificity of triacylglycerols, and to quantify several bioactive compounds of relevant hemp seeds varieties and related taxa. Eight varieties of unhusked hemp seeds and eight samples of commercial husked hemp seeds were studied, and other Cannabaceae seeds: those from hop (Humulus lupulus) and European hackberry (Celtis australis). We found that all hemp seeds varieties constitute a rich source of essential PUFA as linoleic and α-linolenic acids, as well as oleic acid. PUFA were mostly distributed at the sn-2 position of triacylglycerols, thus, being highly bioaccessible, while SFA were mostly located at the sn1,3 positions. The n–6/n–3 PUFA ratio was found to be nutritionally advantageous. Vitamin E compounds were noticeable, and γ-tocopherol was the major tocol found. Regarding phytosterols, campesterol and β-sitosterol were the most prominent compounds, while squalene content was also noticeable. Overall, the lipid fraction of hemp seeds can be considered as a source of essential and bioactive FA as well as an antioxidant- and cholesterollowering bioactive compounds-containing functional food. PB Elsevier SN 0889-1575 YR 2023 FD 2023 LK https://hdl.handle.net/20.500.14352/96731 UL https://hdl.handle.net/20.500.14352/96731 LA eng NO Alonso-Esteban, José Ignacio, María José González-Fernández, Dmitri Fabrikov, María De Cortes Sánchez-Mata, Esperanza Torija-Isasa, y José Luis Guil-Guerrero. «Fatty Acids and Minor Functional Compounds of Hemp (Cannabis Sativa L.) Seeds and Other Cannabaceae Species». Journal of Food Composition and Analysis 115 (enero de 2023): 104962. https://doi.org/10.1016/j.jfca.2022.104962. NO Junta de Andalucía NO Universidad de Almería DS Docta Complutense RD 27 dic 2025