TY - JOUR AU - Alou Cervera, Luis AU - Aguilar, Lorenzo AU - Sevillano Fernández, David AU - Giménez, María José AU - Laguna, Beatriz AU - Echeverría, Olatz AU - Carcas, Antonio AU - Lubomirov, Rubin AU - Casal, Julio AU - Prieto Prieto, José PY - 2005 DO - 10.1093/jac/dki071 SN - 0305-7453 UR - https://hdl.handle.net/20.500.14352/107183 T2 - Journal of Antimicrobial Chemotherapy AB - Objectives: To measure the effect of opsonophagocytosis mediated by complement activated by specific antibodies on the co-amoxiclav serum bactericidal activity against Streptococcus pneumoniae strains with reduced susceptibility to beta-lactams... LA - eng M2 - 742 PB - Oxford University Press KW - β-lactams KW - Phase I study KW - polymorphonuclear neutrophils KW - ex vivo killing curves TI - Effect of opsonophagocytosis mediated by specific antibodies on the co-amoxiclav serum bactericidal activity against Streptococcus pneumoniae after administration of a single oral dose of pharmacokinetically enhanced 2000/125 mg co-amoxiclav to healthy volunteers TY - journal article VL - 55 ER -