TY - JOUR AU - Ikonomopoulou, María AU - López Mancheño, Yaiza AU - Garrido Novelle, Marta AU - Martínez Uña, Maite AU - Gangoda, Lahiru AU - Pal Martin AU - Costa Machado, Luis Filipe AU - Fernández-Marcos, Pablo AU - Ramm, Grant AU - Fernández Rojo, Manuel PY - 2021 DO - 10.1016/j.celrep.2021.108851 SN - 2211-1247 UR - https://hdl.handle.net/20.500.14352/94539 T2 - Cell reports AB - Devil facial tumor disease (DFTD) and its lack of available therapies are propelling the Tasmanian devil population toward extinction. This study demonstrates that cholesterol homeostasis and carbohydrate energy metabolism sustain the proliferation of... LA - eng M2 - 1 PB - Elsevier KW - DFTD KW - Cholesterol KW - Energy metabolism KW - LXR KW - AKT/mTOR KW - Atorvastatin TI - LXR stimulates a metabolic switch and reveals cholesterol homeostasis as a statin target in Tasmanian devil facial tumor disease TY - journal article VL - 34 ER -