RT Journal Article
T1 Nut Allergy in Two Different Areas of Spain: Differences in Clinical and Molecular Pattern
A1 Haroun Díaz, Elisa
A1 Azofra, Julián
A1 González Mancebo, Eloína
A1 Heras, Manuel de las
A1 Pastor Vargas, Carlos
A1 Esteban, Vanesa
A1 Villalba Díaz, María Teresa
A1 Díaz Perales, Araceli
A1 Cuesta Herranz, Javier
AB Introduction: Different clinical and molecular patterns of food allergy have been reported in different areas of the world. The aim of the study is to evaluate differences in allergen patterns among nut-allergic patients in two different areas of Spain.Material and methods: A total of 77 patients with nut allergy from two different regions of Spain (Madrid and Asturias) were evaluated.Results: Hazelnut, peanut, and walnut were the three most frequent nuts eliciting allergy in both regions, but in a different order. Patients from Madrid experienced systemic reactions more often than patients from Asturias (73.5% Madrid vs. 50.0%, p < 0.05). The percentage of sensitizations to LTP (Lipid Transfer Protein) was higher than Bet v 1 (p < 0.05) in the Madrid area. The percentage of sensitizations in Asturias area was similar to LTP than Bet v 1 (Pru p 3 46.4%, Bet v 1 42.9%, ns). Bet v 1 was the predominant allergen involved among hazelnut-allergic patients (56.2%), while LTP was more common in peanut-allergic patients (61.5%).Conclusion: Walnut, hazelnut, and peanut were the most frequent nuts eliciting allergy in Spain. Despite this, important differences in molecular pattern were appreciated not only between both regions, but also among nut-allergic patients in Asturias. The different molecular pattern was linked to the frequency of systemic symptoms.
PB MPDI
SN 2072-6643
YR 2017
FD 2017
LK https://hdl.handle.net/20.500.14352/109061
UL https://hdl.handle.net/20.500.14352/109061
LA eng
NO Haroun-Díaz E, Azofra J, González-Mancebo E, de Las Heras M, Pastor-Vargas C, Esteban V, Villalba M, Díaz-Perales A, Cuesta-Herranz J. Nut Allergy in Two Different Areas of Spain: Differences in Clinical and Molecular Pattern. Nutrients. 2017 Aug 21;9(8):909. doi: 10.3390/nu9080909. PMID: 28825657; PMCID: PMC5579702.
NO Instituto de Salud Carlos III
NO RETIC ARADYAL
DS Docta Complutense
RD 3 abr 2025