TY - JOUR AU - Pérez García, Selene AU - Carrión Caballo, Mar AU - Villanueva Romero, Raúl AU - Hermida Gómez, Tamara AU - Fernández Moreno, Mercedes AU - Mellado, Mario AU - Blanco, Francisco J. AU - Juarranz Moratilla, Yasmina AU - Gomáriz, Rosa P. PY - 2019 DO - 10.1111/jcmm.14283 SN - 1582-1838, ESSN: 1582-4934 UR - https://hdl.handle.net/20.500.14352/13485 T2 - Journal of Cellular and Molecular Medicine AB - Failure of therapeutic approaches for the treatment of osteoarthritis (OA) based on the inhibition of metalloproteinases, might be because of their constitutive expres‐ sion in homeostasis, together with their network complexity. The knowledge of this... LA - eng M2 - 3974 PB - Wiley Open Acces KW - ADAMTS‐12 KW - ADAMTS‐7 KW - COMP KW - Extracellular matrix KW - Osteoarthritis KW - Runx2 synovial fibroblasts KW - Wnt signallingfibroblasts KW - Wnt signalling TI - Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast‐derived ADAMTS‐7 and ‐12 TY - journal article VL - 23 ER -