RT Journal Article
T1 Hospital admissions for community-acquired, ventilator-associated and nonventilator hospital-acquired pneumonia in COPD patients in Spain (2016-2017)
A1 Miguel Díez, Javier De
A1 Albaladejo Vicente, Romana
A1 Hernández Barrera, Valentín
A1 Ji, Zichen
A1 López Herranz, Marta
A1 Jiménez García, Rodrigo
A1 López De Andrés, Ana Isabel
AB Background: To examine the incidence, characteristics and outcomes of community-acquired pneumonia (CAP), ventilator-associated pneumonia (VAP) and nonventilator hospital-acquired pneumonia (NV-HAP) in patients with or without COPD; compare in-hospital outcomes; and identify factors associated with in-hospital mortality (IHM) for pneumonia. Methods: We carried out a retrospective observational study using the hospital discharge records from 2016-17 of the Spanish National Health System. Propensity score matching was used for data analysis. Results: We found 245,905 patients (≥40 years) with pneumonia; we identified CAP in 228,139 patients (19.85% with COPD), VAP in 2,771 patients (8.55% with COPD) and NV-HAP in 14,995 patients (14.17% with COPD). The incidence for the three types of pneumonia was higher in COPD patients (CAP: incidence rate ratio (IRR) 2.23, 95% CI 2.21-2.26; VAP: IRR 1.25, 95% CI 1.08-1.42; and NV-HAP: IRR 1.55, 95% CI 1.48-1.63). The IHM for CAP was 10.35% in COPD patients and 12.91% in the controls (p<0.001). In patients with VAP and NV HAP, IHM was not significantly different between those with and without COPD (43.88% vs. 41.77%;p=0.643 and 29.21% vs. 30.57%;p=0.331, respectively). Factors associated with IHM for all types of pneumonia ana lyzed in COPD patients were older age and receiving dialysis. Conclusions: The incidence of hospitalizations for all types of pneumonia was significantly higher in COPD patients than in the non-COPD population. In contrast, IHM was significantly lower among COPD patients with CAP than among matched non-COPD patients. Higher mortality rates in COPD patients with any pneumonia type were associated with increasing age and receiving dialysis.
PB Elsevier
SN 0953-6205
YR 2020
FD 2020-06-25
LK https://hdl.handle.net/20.500.14352/100648
UL https://hdl.handle.net/20.500.14352/100648
LA eng
NO de Miguel-Diez J, Albaladejo-Vicente R, Hernández-Barrera V, Ji Z, Lopez-Herranz M, Jimenez-Garcia R, López-de-Andrés A. Hospital admissions for community-acquired, ventilator-associated and nonventilator hospital-acquired pneumonia in COPD patients in Spain (2016-2017). Eur J Intern Med. 2020 Sep;79:93-100. doi: 10.1016/j.ejim.2020.06.028. Epub 2020 Jun 30. PMID: 32616338.
NO Sociedad Española de Neumología y Cirugía Torácica
NO Sociedad Madrileña de Neumología y Cirugía de Tórax
NO Instituto de Salud Carlos III
NO Fondo Europeo de Desarrollo Regional
DS Docta Complutense
RD 5 abr 2025