TY - JOUR AU - Municio, Cristina AU - Dominguez-Soto, Ángeles AU - Fuentelsaz-Romero, Sara AU - Lamana Domínguez, Amalia AU - Montes, Nuria AU - Cuevas, Víctor AU - García Campos. Raquel AU - Pablos Álvarez, José Luis AU - González-Álvaro, Isidoro AU - Puig-Kröger, Amaya PY - 2018 DO - 10.1136/annrheumdis-2017-212537 SN - 0003-4967 UR - https://hdl.handle.net/20.500.14352/94316 T2 - Annals of Rheumatic Diseases AB - OBJECTIVES: Methotrexate (MTX) is the anchor drug for treatment of rheumatoid arthritis (RA), but the mechanism of its anti-inflammatory action is not fully understood. In RA, macrophages display a proinflammatory polarisation profile that resembles... LA - eng M2 - 752 PB - BMJ Publishing Group TI - Methotrexate limits inflammation through an A20-dependent cross-tolerance mechanism TY - journal article VL - 77 ER -