RT Journal Article
T1 Dipole density of low-frequency and spike magnetic activity: A reliable procedure in presurgical evaluation of temporal lobe epilepsy
A1 Fernández Lucas, Alberto Amable
A1 de Sola, Rafael G.
A1 Amo, Carlos
A1 Turrero Nogués, Agustín
A1 Zuluaga Arias, María del Pilar
A1 Maestu Unturbe, Fernando
A1 Campo, Pablo
A1 Ortiz, Tomás
AB Conventional visual analysis and dipole density analysis of magnetoencephalographic data for both spike and low-frequency magnetic activity were compared for presurgical evaluation in temporal lobe epilepsy (TLE) in a sample of 26 drug-resistant operated TLE patients. A series of logistic regression analyses were performed. Dipole density sensitivity was superior to visual localization analysis. Three separated logistic models were calculated for interictal spikes, low-frequency magnetic activity, and the combination of both measures. A combined interictal spike/low-frequency magnetic activity model predicted correctly the operated temporal lobe in all patients. Clear-cut criteria for the probability model are proposed that are valid for 92.3% of cases in the sample. The quantitative approach proposed by this study is an evidence-based model for presurgical evaluation of temporal lobe epilepsy, which improves previous magnetoencephalographic investigations and establishes working clinical criteria for patient evaluation in TLE.
PB American Clinical Neurophysiology Society
SN 0736-0258
YR 2004
FD 2004-07
LK https://hdl.handle.net/20.500.14352/51438
UL https://hdl.handle.net/20.500.14352/51438
NO Fernández Lucas, A. A., De Sola, R. G., Amo, C. et al. «Dipole Density of Low-Frequency and Spike Magnetic Activity: A Reliable Procedure in Presurgical Evaluation of Temporal Lobe Epilepsy»: Journal of Clinical Neurophysiology, vol. 21, n.o 4, julio de 2004, pp. 254-66. DOI.org (Crossref), https://doi.org/10.1097/00004691-200407000-00004.
DS Docta Complutense
RD 17 abr 2025