TY  - JOUR
AU  - Burgos, Daniel 
AU  - Machío-Castello, María
AU  - Iglesias-Cabeza, Nerea
AU  - Giráldez, Beatriz 
AU  - González Fernández, Juan
AU  - Sánchez-Martín, Gema
AU  - Sánchez, Marina 
AU  - Serratosa, José 
PY  - 2022
DO  - 10.1007/s13311-022-01304-w
SN  - 1933-7213
UR  - https://hdl.handle.net/20.500.14352/94060
T2  - Neurotherapeutics
AB  - Lafora disease is a fatal form of progressive myoclonic epilepsy caused by mutations in the EPM2A or NHLRC1/EPM2B genes that usually appears during adolescence. The Epm2a−/− and Epm2b−/− knock-out mouse models of the disease develop behavioral and...
LA  - eng
M2  - 230
PB  - Elsevier
KW  - Lafora disease
KW  - Epilepsy
KW  - Mouse models
KW  - Metformin
KW  - Drug repurposing
KW  - Early treatment
TI  - Early Treatment with Metformin Improves Neurological Outcomes in Lafora Disease
TY  - journal article
VL  - 20
ER  -