RT Journal Article T1 The microbiome as a human organ A1 Baquero, Fernando A1 Nombela, César AB The human organism is a complex structure composed of cells belonging to all three domains of life on Earth, Eukarya, Bacteria and Archaea, as well as their viruses. Bacterial cells of more than a thousand taxonomic units are condensed in a particular functional collective domain, the intestinal microbiome. The microbiome constitutes the last human organ under active research. Like other organs, and despite its intrinsic complexity, the microbiome is readily inherited, in a process probably involving ‘small world’ power law dynamics of construction in newborns. Like any other organ, the microbiome has physiology and pathology, and the individual (and collective?) health might be damaged when its collective population structure is altered. The diagnostic of microbiomic diseases involves metagenomic studies. The therapeutics of microbiome-induced pathology include microbiota transplantation, a technique increasingly available. PB European Society of Clinical Microbiology and Infectious Diseases YR 2012 FD 2012 LK https://hdl.handle.net/20.500.14352/43848 UL https://hdl.handle.net/20.500.14352/43848 LA eng NO Comunidad de Madrid NO Unión Europea. FP7 NO Ministerio de Ciencia e Innovación (MICINN) DS Docta Complutense RD 10 abr 2025