RT Journal Article
T1 WRKY6 Transcription Factor Restricts Arsenate Uptake and Transposon Activation in Arabidopsis
A1 Castrillo, Gabriel
A1 Sánchez-Bermejo, Eduardo
A1 Lorenzo, Laura de
A1 Crevillén, Pedro
A1 Fraile-Escanciano, Ana
A1 TC, Mohan
A1 Mouriz, Alfonso
A1 Catarecha, Pablo
A1 Sobrino Plata, Juan
A1 Olsson, Sanna
A1 Leo del Puerto, Yolanda
A1 Mateos, Isabel
A1 Rojo, Enrique
A1 Hernández, Luis
A1 Jarillo, Jose
A1 Piñeiro, Manuel
A1 Paz-Ares, Javier
A1 Leyva, Antonio
AB Stress constantly challenges plant adaptation to the environment. Of all stress types, arsenic was a major threat during the early evolution of plants. The most prevalent chemical form of arsenic is arsenate, whose similarity to phosphate renders it easily incorporated into cells via the phosphate transporters. Here, we found that arsenate stress provokes a notable transposon burst in plants, in coordination with arsenate/phosphate transporter repression, which immediately restricts arsenate uptake. This repression was accompanied by delocalization of the phosphate transporter from the plasma membrane. When arsenate was removed, the system rapidly restored transcriptional expression and membrane localization of the transporter. We identify WRKY6 as an arsenate-responsive transcription factor that mediates arsenate/phosphate transporter gene expression and restricts arsenate-induced transposon activation. Plants therefore have a dual WRKY-dependent signaling mechanism that modulates arsenate uptake and transposon expression, providing a coordinated strategy for arsenate tolerance and transposon gene silencing.
PB Oxford University Press
SN 1040-4651
YR 2013
FD 2013
LK https://hdl.handle.net/20.500.14352/99288
UL https://hdl.handle.net/20.500.14352/99288
LA eng
NO Gabriel Castrillo, Eduardo Sánchez-Bermejo, Laura de Lorenzo, Pedro Crevillén, Ana Fraile-Escanciano, Mohan TC, Alfonso Mouriz, Pablo Catarecha, Juan Sobrino-Plata, Sanna Olsson, Yolanda Leo del Puerto, Isabel Mateos, Enrique Rojo, Luis E. Hernández, Jose A. Jarillo, Manuel Piñeiro, Javier Paz-Ares, Antonio Leyva, WRKY6 Transcription Factor Restricts Arsenate Uptake and Transposon Activation in Arabidopsis  , The Plant Cell, Volume 25, Issue 8, August 2013, Pages 2944–2957, https://doi.org/10.1105/tpc.113.114009
DS Docta Complutense
RD 7 abr 2025