RT Journal Article
T1 Exploratory Analysis of Power Spectrum and Functional Connectivity During Resting State in Young Binge Drinkers: A MEG Study
A1 Correas Marín, María De Los Ángeles
A1 Rodriguez Holguín, Socorro
A1 Cuesta, Pablo
A1 López-Caneda, Eduardo
A1 García Moreno, Luis Miguel
A1 Cadaveira, Fernando
A1 Maestu Unturbe, Fernando
AB Binge Drinking (BD) is a pattern of intermittent intensive alcohol intake which has spread among young adults over the last decades. Adolescence constitutes a critical neuromaturation period in which the brain is particularly sensitive to the effects of alcohol. However, little is known about how BD affects the brain activity. This study aimed to characterize the brain's functional organization in BD and non-BD young population by means of analyzing functional connectivity (FC) and relative power spectra (PS) profiles measured with magnetoencephalography (MEG) during eyes-closed resting state. Our sample composed 73 first-year university students (35 BDs and 38 controls). Results showed that the BD subjects displayed a decreased alpha FC in frontal-parietal regions, and conversely, an enhanced FC in the delta, theta and beta bands in fronto-temporal networks. Besides the FC differences, the BD group showed a decreased PS within alpha range and an increased PS within theta range in the brain's occipital region. These differences in FC and PS measurements provide new evidence of the neurophysiological alterations related to the alcohol neurotoxicity and could represent an initial sign of an anomalous neural activity caused by a BD pattern of alcohol consumption during youth.
PB World Scientific Publishing
SN 0129-0657
SN 1793-6462
YR 2015
FD 2015
LK https://hdl.handle.net/20.500.14352/95160
UL https://hdl.handle.net/20.500.14352/95160
LA eng
NO A. Correas (Spain), S. Rodriguez Holguín (Spain), P. Cuesta (Spain), E. López-Caneda (Spain), L. M. García-Moreno (Spain), F. Cadaveira (Spain), and F. Maestú (Spain). Exploratory Analysis of Power Spectrum and Functional Connectivity During Resting State in Young Binge Drinkers: A MEG StudyInternational Journal of Neural Systems 2015 25:03
DS Docta Complutense
RD 18 abr 2025