RT Journal Article T1 Effect of COVID-19 lockdown in Spain on structural andfunctional outcomes of Neovascular AMD patients A1 Valverde Megías, Alicia A1 Rego Lorca, Daniela A1 Fernández Vigo, José Ignacio A1 Murciano Cespedosa, Antonio A1 Megías Fresno, Alicia A1 García Feijoo, Julián AB This is a retrospective single-center study of patients with neovascular age-related macular degeneration whose follow-up was delayed due to COVID-19 pandemic with at least three months between visits in Madrid, Spain. The purpose of the study was to evaluate best corrected visual acuity (BCVA) changes and try to identify features in optical coherence tomography (OCT) that could be related to more profound visual loss. It included 270 eyes. The two last visits before lockdown were used for comparison with the visit after lockdown. BCVA changed from 60.2 ± 18.2 to 55.9 ± 20.5 ETDRS letters. 29% of the eyes lost more than 5 letters. OCT was active in 67% of eyes before lockdown and in 80.4% after lockdown. Multiple lineal analysis showed that patients whose OCT before lockdown presented with a combination of intra and subretinal fluid were more likely to suffer a greater visual loss (p = 0.002). These patients should be encouraged to not miss any visits in case a new lockdown is imposed. PB Electronic: 2077-0383 SN Electronic: 2077-0383 YR 2021 FD 2021-08-12 LK https://hdl.handle.net/20.500.14352/4768 UL https://hdl.handle.net/20.500.14352/4768 LA eng DS Docta Complutense RD 13 abr 2025