RT Journal Article T1 Efficacy of technology-based interventions in psychosis: a systematic review and network meta-analysis A1 Morales Pillado, Carla A1 Fernández Castilla, Belén A1 Sánchez Gutiérrez, Teresa A1 González Fraile, Eduardo A1 Barbeito, Sara A1 Calvo, Ana AB BackgroundTechnology-based interventions (TBIs) are a useful approach when attempting to provide therapy to more patients with psychosis.MethodsRandomized controlled trials of outcomes of TBIs v. face-to-face interventions in psychosis were identified in a systematic search conducted in PubMed/Ovid MEDLINE. Data were extracted independently by two researchers, and standardized mean changes were pooled using a three-level model and network meta-analysis.ResultsFifty-eight studies were included. TBIs complementing treatment as usual (TAU) were generally superior to face-to-face interventions (g = 0.16, p ≤ 0.0001) and to specific outcomes, namely, neurocognition (g = 0.13, p ≤ 0.0001), functioning (g = 0.25, p = 0.006), and social cognition (g = 0.32, p ≤ 0.05). Based on the network meta-analysis, the effect of two TBIs differed significantly from zero; these were the TBIs cognitive training for the neurocognitive outcome [g = 0.16; 95% confidence interval (CI) 0.09–0.23] and cognitive behavioral therapy for quality of life (g = 1.27; 95% CI 0.46–2.08). The variables educational level, type of medication, frequency of the intervention, and contact during the intervention moderated the effectiveness of TBIs over face-to-face interventions in neurocognition and symptomatology.ConclusionsTBIs are effective for the management of neurocognition, symptomatology, functioning, social cognition, and quality of life outcomes in patients with psychosis. The results of the network meta-analysis showed the efficacy of some TBIs for neurocognition, symptomatology, and quality of life. Therefore, TBIs should be considered a complement to TAU in patients with psychosis. PB Cambridge University Press SN 0033-2917 YR 2022 FD 2022-12-06 LK https://hdl.handle.net/20.500.14352/72922 UL https://hdl.handle.net/20.500.14352/72922 LA eng NO CRUE-CSIC (Acuerdos Transformativos 2022) NO MINECO NO Fundación Alicia a Koplowitz DS Docta Complutense RD 2 may 2024