RT Journal Article
T1 The Synergistic Effect of Quince Fruit and Probiotics (Lactobacillus and Bifidobacterium) on Reducing Oxidative Stress and Inflammation at the Intestinal Level and Improving Athletic Performance during Endurance Exercise
A1 Herrera Rocha, Karen Marlenne
A1 Manjarrez Juanes, María Magdalena
A1 Larrosa Pérez, María Del Mar
A1 Barrios Payán, José Alberto
A1 Rocha Guzmán, Nuria Elizabeth
A1 Macía Salas, Alejo
A1 Gallegos Infante, José Alberto
A1 Alberto Álvarez, Saul
A1 González Laredo, Rubén Francisco
A1 Moreno Jiménez, Martha Rocío
AB Endurance exercise promotes damage at the intestinal level and generates a variety of symptoms related to oxidative stress processes, inflammatory processes, microbiota dysbiosis, and intestinal barrier damage. This study evaluated the effects of quince (Cydonia oblonga Mill.) and probiotics of the genera Lactobacillus and Bifidobacterium on intestinal protection and exercise endurance in an animal swimming model. Phytochemical characterization of the quince fruit demonstrated a total dietary fiber concentration of 0.820 ± 0.70 g/100 g and a fiber-bound phenolic content of 30,218 ± 104 µg/g in the freeze-dried fruit. UPLC-PDA-ESI-QqQ analyses identified a high content of polyphenol, mainly flavanols, hydroxycinnamic acids, hydroxybenzoic acids, flavonols, and, to a lesser extent, dihydrochalcones. The animal model of swimming was performed using C57BL/6 mice. The histological results determined that the consumption of the synbiotic generated intestinal protection and increased antioxidant (catalase and glutathione peroxidase enzymes) and anti-inflammatory (TNF-α and IL-6 and increasing IL-10) activities. An immunohistochemical analysis indicated mitochondrial biogenesis (Tom2) at the muscular level related to the increased swimming performance. These effects correlated mainly with the polyphenol content of the fruit and the effect of the probiotics. Therefore, this combination of quince and probiotics could be an alternative for the generation of a synbiotic product that improves exercise endurance and reduces the effects generated by the practice of high performance sports.
PB MDPI
YR 2023
FD 2023-11-13
LK https://hdl.handle.net/20.500.14352/104089
UL https://hdl.handle.net/20.500.14352/104089
LA eng
NO Herrera-Rocha, K. M., Manjarrez-Juanes, M. M., Larrosa, M., Barrios-Payán, J. A., Rocha-Guzmán, N. E., Macías-Salas, A., Gallegos-Infante, J. A., Álvarez, S. A., González-Laredo, R. F., & Moreno-Jiménez, M. R. (2023). The Synergistic Effect of Quince Fruit and Probiotics (Lactobacillus and Bifidobacterium) on Reducing Oxidative Stress and Inflammation at the Intestinal Level and Improving Athletic Performance during Endurance Exercise. Nutrients, 15(22), 4764. https://doi.org/10.3390/nu15224764
NO 2022 Descuento MDPI
NO Tecnológico Nacional de México
DS Docta Complutense
RD 7 abr 2025