TY - JOUR AU - Gómez Almería, Marta AU - Martinez Gonzalez, Loreto AU - Matos, Ana Teresa AU - Rodríguez Cueto, Carmen Aurora AU - Vaz, Ana Rita AU - Martín Baquero, Raquel AU - Pérez de la Lastra, Carmen AU - Infantes, Rafael AU - Fernández Ruiz, José Javier AU - Palomo, Valle AU - Gil, Carmen AU - Brites, Dora AU - Martinez, Ana AU - Lago Femia, Eva De PY - 2025 DO - 10.1016/j.neuropharm.2025.110804 SN - 0028-3908 UR - https://hdl.handle.net/20.500.14352/131162 T2 - Neuropharmacology AB - Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease for which no effective treatments currently exist. The FDA and EMA have approved only riluzole, a drug that modestly extends patient survival by 3-18 months. In our... LA - eng PB - Elsevier KW - Amyotrophic lateral sclerosis KW - Neuroinflammation KW - Neuroprotection KW - miRNAs KW - Protein kinase inhibitor KW - Riluzole KW - Combinatory therapy KW - TDP-43 TI - Assessment of the therapeutic effect ofigs2.7, a ck1δ protein kinase inhibitor, in combination with riluzole for the treatment of als-associated tdp-43 proteinopathy TY - journal article VL - 285 ER -