TY  - JOUR
AU  - Gómez García, Ricardo
AU  - Núñez Fernández, Lucía
AU  - Caballero Collado, Ricardo
AU  - Vaquero González, Luis Miguel
AU  - Tamargo Menéndez, Juan
AU  - Delpón Mosquera, María Eva
PY  - 2005
DO  - 10.1038/sj.bjp.0706302
SN  - 0007–1188
UR  - https://hdl.handle.net/20.500.14352/91707
AB  - Both spironolactone (SP) and its main metabolite, canrenoic acid (CA), prolong cardiac action potential duration and decrease the Kv11.1 (HERG) current. We examined the effects of SP and CA on cardiac hKv1.5, Kv4.3 and Kv7.1+minK channels that...
LA  - eng
M2  - 146
PB  - Wiley
KW  - Spironolactone
KW  - canrenoic acid
KW  - cardiac potassiumchannels
KW  - hKv1.5
KW  - Kv4.3
KW  - Kv7.1þminK
KW  - patch clamp
KW  - repolarisation
TI  - Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels
TY  - journal article
VL  - 146
ER  -