TY  - JOUR
AU  - Priego, Neibla
AU  - Arechederra, María
AU  - Sequera Hurtado, Celia
AU  - Bragado Domingo, Paloma
AU  - Vázquez-Carballo, Ana
AU  - Gutiérrez Uzquiza, Álvaro
AU  - Martín-Granado, Víctor
AU  - Ventura, Juan José
AU  - Kazanietz, Marcelo G.
AU  - Carmen Guerrero, Marcelo G.
AU  - Porras Gallo, María Almudena
PY  - 2016
DO  - 10.18632/oncotarget.9911
SN  - 1949-2553
UR  - https://hdl.handle.net/20.500.14352/115809
T2  - Oncotarget
AB  - C3G, a Guanine nucleotide Exchange Factor (GEF) for Rap1 and R-Ras, has been shown to play important roles in development and cancer. Previous studies determined that C3G regulates cell death through down-regulation of p38α MAPK activity. Here, we...
LA  - eng
M2  - 45060
KW  - C3G
KW  - p38 MAPK
KW  - Rap1
KW  - migration
KW  - tumorigenesis
TI  - C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
TY  - journal article
VL  - 7
ER  -