TY - JOUR AU - Aix, Esther AU - Gutiérrez-Gutiérrez, Óscar AU - Sánchez-Ferrer, Carlota AU - Aguado Sánchez, Tania AU - Flores, Ignacio PY - 2016 DO - 10.1083/jcb.201510091 SN - 0021-9525 UR - https://hdl.handle.net/20.500.14352/91537 T2 - Journal of Cell Biology AB - The molecular mechanisms that drive mammalian cardiomyocytes out of the cell cycle soon after birth remain largely unknown. Here, we identify telomere dysfunction as a critical physiological signal for cardiomyocyte cell-cycle arrest. We show that... LA - eng M2 - 571 PB - Rockefeller University Press KW - Cell cycle and division KW - DNA biology TI - Postnatal telomere dysfunction induces cardiomyocyte cell-cycle arrest through p21 activation TY - journal article VL - 213 ER -