%0 Journal Article
%A Ferrándiz,  María José
%A Ardanuy, Carmen
%A Linares, Josefina
%A Balsalobre, Luz
%A García Esteban, María Teresa
%A G. de la Campa, Adela
%T New species genetic approach to identify strains of mitis group Streptococci that are donors of rifampin resistance to Streptococcus pneumoniae
%D 2011
%@ 0066-4804
%U https://hdl.handle.net/20.500.14352/125414
%X Eight rifampin-resistant streptococci of the mitis group were identified at the species level by using a concatenated 16S rRNA gene-sodA-rpoB-hlpA sequence. Characterization of their rpoB alleles showed single amino acid changes involved in rifampin resistance. Comparison of RpoB sequences from pneumococcal recombinant isolates, viridans isolates, and type strains revealed a species-specific amino acid signature, which allowed it to be ascertained that recombinant RpoBs were originated in genetic interchanges with Streptococcus mitis and Streptococcus oralis.
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