%0 Journal Article
%A Alou Cervera, Luis
%A Gómez Rubio, Elena
%A Giménez Mestre, María José
%A Álvaro Afonso, Francisco Javier
%A Coronel, Pilar
%A Sevillano Fernández, David
%T Exploring therapeutic options for mild diabetic-related foot infections: a comparative in vitro study of cefditoren versus amoxicillin/clavulanic acid
%D 2024
%@ 0214-3429
%@ 1988-9518
%U https://hdl.handle.net/20.500.14352/106087
%X Skin and soft tissue infections (SSTIs), and particularly diabetic-related foot infections (DFI), present diagnostic and therapeutic complexities, often leading to severe complications.This study aims to evaluate the in vitro efficacy of cefditoren and amoxicillin/clavulanic acid against typical DFI pathogens. Clinical samples from 40 patients with mild SSTIs wereanalyzed, revealing a predominance of Staphylococcus spp. and Streptococcus spp. species. Cefditoren exhibited activity against 90% of isolates, with superior potency over amoxicillin/clavulanic acid. These findings underscore the utility of cefditoren in empirical treatment of DFI, although a larger sample size would be desirable for further validation.
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