RT Journal Article
T1 Analyses of transcutaneous oxygen pressure values stratified for foot angiosomes to predict diabetic foot ulcer healing
T2 Analisis de los valores de presion transcutanea de oxigeno estratificado por los angiosomas del pie
A1 López-Moral M, 
A1 García-Madrid Martín De Almagro, Marta
A1 Molines Barroso, Raúl Juan
A1 García Álvarez, Yolanda
A1 Tardaguila García, Aroa
A1 Lázaro Martínez, José Luis
A2 Elsevier, 
AB Aims: Previous research suggested that diabetic foot ulcer (DFU) location could affect transcutaneous oxygen pressure (TcPO2) values following the angiosome concept. Up to our knowledge no studies have yet analyzed if the location of a diabetic foot ulcer can be a confounding factor that modifies TcPO2 values. The primary aim of this study was to compare the potential healing prognosis of TcPO2 differentiated for diabetic foot ulcers in different angiosome locations. Methods: a 2-years observational cohort prospective study was performed in 81 patients with diabetic foot ulcers. Transcutaneous oxygen pressure measurements were performed at baseline by placing the electrode on two different angiosomes: dorsal zone of the foot (dorsalis pedis angiosome) and between the navicular bone and the tibial malleolus (posterior tibial angiosome). The main outcome was establishing the effectiveness of TcPO2 measurements (dorsalis pedis angiosome and posterior tibial angiosome) for predicting DFU healing. Results: Transcutaneous oxygen pressure probe placed in the dorsum of the foot (dorsalis pedis angiosome) yielded a sensitivity (S) of 95 % and specificity (SP) of 73 %, and an area under the curve (AUC) of 0.902 (p < 0.001 [0.84–0.96]) for ulcers located in the forefoot and toes; while TcPO2 placed in the posterior tibial angiosome yielded an S of 100 % and SP of 85 % and an AUC of 0.894 (p <0.001 [0-822-0.966]) for DFU located in the midfoot and heel. Conclusion: This study suggests that angiosome-guided TcPO2 contributes to a prognosis of successful foot ulcer healing.
PB Elsevier
YR 2023
FD 2023-10-08
LK https://hdl.handle.net/20.500.14352/91714
UL https://hdl.handle.net/20.500.14352/91714
LA eng
NO López-Moral M, García-Madrid M, Molines-Barroso RJ, García-Álvarez Y, Tardáguila-García A, Lázaro-Martínez JL. Analyses of transcutaneous oxygen pressure values stratified for foot angiosomes to predict diabetic foot ulcer healing. J Tissue Viability. 2023 Oct 10:S0965-206X(23)00106-7. doi: 10.1016/j.jtv.2023.10.003. Epub ahead of print. PMID: 37838592.
DS Docta Complutense
RD 9 abr 2025