TY  - JOUR
AU  - Materna, Marie
AU  - Cárdenas Mastrascusa, Paula Patricia
AU  - Regueiro González-Barros, José Ramón
AU  - Béziat, Vivien
PY  - 2024
DO  - 10.1126/science.adh4059
SN  - 0036-8075
UR  - https://hdl.handle.net/20.500.14352/107408
T2  - Science
AB  - We describe humans with rare biallelic loss-of-function PTCRA variants impairing pre-TCRα expression. Low circulating naïve αβ T cell counts at birth persisted over time, with normal memory αβ and high γδ T cell counts. Their TCRα repertoire was...
LA  - eng
PB  - American Association for the Advancement of Science
TI  - The immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
TY  - journal article
VL  - 383
ER  -