RT Journal Article
T1 Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At-Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers
A1 Bravo, Laura
A1 Martínez López, Sara
A1 Sierra Cinos, José Luis
A1 Mateos Briz, María Raquel
A1 Sarriá Ruiz, Beatriz Irene
AB Yerba mate has been reported to have antihypertensive, hypocholesterolemic, antidiabetic, or antiobesity properties. Most evidences from human trials involved intakes of high amounts of mate by habitual consumers. Considering its increasing popularity, this study aimed at assessing the potential cardiometabolic effects of moderate intake of yerba mate by nonhabitual consumers. A randomized, crossover, controlled study was carried out in healthy and hypercholesterolemic subjects. Anthropometric parameters, blood pressure, blood lipids, glucose metabolism, inflammatory cytokines, chemokines, and different markers of endothelial function, as well as incretins, adipocytokines, and different hormones were measured at baseline and after 8 weeks consuming yerba mate or a decaffeinated isotonic drink (control). After daily consumption of three servings of mate tea, blood pressure, inflammatory cytokines, chemokines, and colony-stimulating factors decreased in all participants. LDL-C decreased in normocholesterolemic individuals, while the mate and control interventions elicited similar hypolipidemic action in the hypercholesterolemic group. Ghrelin and glucose-dependent insulinotropic polypeptide (GIP) significantly decreased after mate intake, while glucagon-like peptide 1 (GLP-1) and adipocytokines remained unchanged. Body fat percentage and tricipital skinfold decreased only in healthy subjects, with no effects on total body weight. In conclusion, yerba mate could exert cardiometabolic protective effects in healthy consumers and in subjects at moderate cardiovascular risk.
PB Wiley
YR 2025
FD 2025
LK https://hdl.handle.net/20.500.14352/120541
UL https://hdl.handle.net/20.500.14352/120541
LA eng
NO Bravo, L., Martínez‐López, S., Sierra‐Cinos, J. L., Mateos, R., & Sarriá, B. (2025). Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At‐Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers. Molecular Nutrition & Food Research, e70065.
NO Ministerio de Economía y Competitividad (España)
NO Agencia Estatal de Investigación
DS Docta Complutense
RD 15 dic 2025