TY  - JOUR
AU  - Pachón Angona, Irene
AU  - Bernard, Paul J.
AU  - Simakov, Alexey
AU  - Maj, Maciej
AU  - Jozwiak, Krzysztof
AU  - Novotna, Anna
AU  - Lemke, Carina
AU  - Gütschow, Michael
AU  - Martin, Helene
AU  - Oset Gasque, María Jesús
AU  - Contelles, José Marco
AU  - Ismaili, Lhassane
PY  - 2024
DO  - 10.3390/pharmaceutics16010121
SN  - 1999-4923
UR  - https://hdl.handle.net/20.500.14352/111903
T2  - Pharmaceutics
AB  - This work relates to the design and synthesis of a series of novel multi-target directed ligands (MTDLs), i.e., compounds 4a–l, via a convenient one-pot three-component Hantzsch reaction. This approach targeted calcium channel antagonism, antioxidant...
LA  - eng
M2  - 1
PB  - MDPI
KW  - Calcium channel inhibitors
KW  - Proteases inhibitors
KW  - Antioxidant response element
KW  - ORAC
KW  - Alzheimer’s disease
TI  - Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties
TY  - journal article
VL  - 16
ER  -