RT Journal Article
T1 Development of the mandibular condylar cartilage in human specimens of 10–15 weeks’ gestation
A1 Mérida Velasco, José Ramón
A1 Rodríguez Vázquez, José Francisco
A1 Cuadra Blanco, Crótida De La
A1 Campos López, R.
A1 Sánchez Montesinos, Indalecio
A1 Mérida Velasco, Juan Antonio
AB This study analyses some morphological and histological aspects that could have a role in the development of the condylar cartilage (CC). The specimens used were serial sections from 49 human fetuses aged 10-15 weeks. In addition, 3D reconstructions of the mandibular ramus and the CC were made from four specimens. During weeks 10-11 of development, the vascular canals (VC) appear in the CC and the intramembranous ossification process begins. At the same time, in the medial region of the CC, chondroclasts appear adjacent to the vascular invasion and to the cartilage destruction. During weeks 12-13 of development, the deepest portion of the posterolateral vascular canal is completely surrounded by the hypertrophic chondrocytes. The latter emerge with an irregular layout. During week 15 of development, the endochondral ossification of the CC begins. Our results suggest that the situation of the chondroclasts, the posterolateral vascular canal and the irregular arrangement of the hypertrophic chondrocytes may play a notable role in the development of the CC.
PB Wiley
SN 0021-8782
YR 2008
FD 2008-12-30
LK https://hdl.handle.net/20.500.14352/112521
UL https://hdl.handle.net/20.500.14352/112521
LA eng
NO Mérida Velasco JR, Rodríguez Vázquez JF, De la Cuadra Blanco C, Campos López R, Sánchez M, Mérida Velasco JA. Development of the mandibular condylar cartilage in human specimens of 10-15 weeks' gestation. J Anat. 2009 Jan;214(1):56-64. doi: 10.1111/j.1469-7580.2008.01009.x
DS Docta Complutense
RD 24 abr 2025