RT Journal Article
T1 Lettuce Allergy Is a Lipid Transfer Syndrome-Related Food Allergy With a High Risk of Severe Reactions
A1 Muñoz-García, E
A1 Luengo-Sánchez, O
A1 Moreno-Pérez, N
A1 Cuesta-Herranz, J
A1 Pastor Vargas, Carlos
A1 Cardona, V
AB Background and objective: Lipid transfer protein (LTP) sensitization is the most common cause of food allergy in the Mediterranean area, with peach allergy acting as the primary sensitizer in most cases. Lettuce has been described as a common offending food in patients with LTP syndrome. The aim of the study was to investigate the frequency and clinical expression of LTP syndrome in a sample of lettuceallergic patients.Methods: We determined specific IgE to Pru p 3 and lettuce in a sample of 30 patients with a diagnosis of lettuce allergy. Symptoms elicited by other LTP-containing plant-derived foods and the presence of cofactors were assessed.Results: The clinical symptoms of lettuce allergy were frequently severe, with 18 of the 30 patients experiencing anaphylaxis. All the patients had allergic reactions to other plant foods. Cofactors were involved in the clinical reactions of 13 of the 30 patients. Sensitization to pollens was found in 90% of patients.Conclusions: Lettuce allergy is found not as an isolated condition but in the context of LTP syndrome and it is characterized by severe reactions and frequent cofactor association.
PB Esmon
SN 1018-9068
YR 2017
FD 2017-04-10
LK https://hdl.handle.net/20.500.14352/108295
UL https://hdl.handle.net/20.500.14352/108295
LA eng
NO Muñoz-García E, Luengo-Sánchez O, Moreno-Pérez N, Cuesta-Herranz J, Pastor-Vargas C, Cardona V. Lettuce Allergy Is a Lipid Transfer Syndrome-Related Food Allergy With a High Risk of Severe Reactions. J Investig Allergol Clin Immunol. 2017;27(2):98-103. doi: 10.18176/jiaci.0110. Epub 2016 Sep 9. PMID: 27609533.
DS Docta Complutense
RD 18 abr 2025