RT Journal Article
T1 Morphogenesis of the juxtaoral organ in humans
A1 Sánchez‐Montesinos, I.
A1 Rodríguez Vázquez, José Francisco
A1 Cuadra Blanco, Crótida De La
A1 Salmerón Escobar, José Ignacio
A1 Mérida Velasco, José Ramón
AB The juxtaoral organ was studied using light microscopy in 55 human embryos and 90 fetuses at different stages of development. The juxtaoral organ arises from the epithelium at the bottom of the transverse opening of the primitive mouth during O'Rahilly stage 16 and becomes detached from the epithelium after O'Rahilly stage 18. The juxtaoral organ is innervated by the buccal nerve from O'Rahilly stage 20 onward, and its connective tissue capsule is clearly visible after week 11 of development. This study enabled us to describe three main periods of juxtaoral organ development: (1) the period of epithelial condensation and invagination, at O'Rahilly stages 16-17; (2) the period during which the juxtaoral organ becomes detached from the oral epithelium and is innervated, at O'Rahilly stages 18-23; and (3) the period during which the connective tissue capsule is formed, after week 11 of development. We also analysed the juxtaoral organ of five additional fetuses by immunohistochemistry with anti-NF-200 to verify their innervation. The results show that the juxtaoral organ may have a function in the mechanical activity of the region.
PB Wiley
SN 0021-8782
SN 1469-7580
YR 2005
FD 2005-02
LK https://hdl.handle.net/20.500.14352/112569
UL https://hdl.handle.net/20.500.14352/112569
LA eng
NO Mérida-Velasco JR, Rodríguez-Vázquez JF, de la Cuadra-Blanco C, Salmerón JI, Sánchez-Montesinos I, Mérida-Velasco JA. Morphogenesis of the juxtaoral organ in humans. J Anat. 2005 Feb;206(2):155-63. doi: 10.1111/j.1469-7580.2005.00377.x. PMID: 15730480; PMCID: PMC1571462.
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 9 abr 2025