RT Journal Article
T1 Minimal Residual Disease Monitoring with Next-Generation Sequencing Methodologies in Hematological Malignancies
A1 Sánchez, Ricardo
A1 Ayala Díaz, Rosa María
A1 Martínez López, Joaquín
AB Ultra-deep next-generation sequencing has emerged in recent years as an important diagnostic tool for the detection and follow-up of tumor burden in most of the known hematopoietic malignancies. Meticulous and high-throughput methods for the lowest possible quantified disease are needed to address the deficiencies of more classical techniques. Precision-based approaches will allow us to correctly stratify each patient based on the minimal residual disease (MRD) after a treatment cycle. In this review, we consider the most prominent ways to approach next-generation sequencing methodologies to follow-up MRD in hematological neoplasms.
PB MDPI
SN 1422-0067
YR 2019
FD 2019-06-10
LK https://hdl.handle.net/20.500.14352/12572
UL https://hdl.handle.net/20.500.14352/12572
LA eng
DS Docta Complutense
RD 6 sept 2024