RT Journal Article
T1 Weight Regain Outcomes After Bariatric Surgery in the Long-term Follow-up: Role of Preoperative Factors
A1 Torrego-Ellacuría, Macarena
A1 Larrad-Sainz, Angélica
A1 Hernández-Nuñez, Gemma Maria
A1 Marcuello, Clara
A1 Rubio Herrera, Miguel Ángel
A1 Barabash Bustelo, Ana
A1 Matía Martín, María Del Pilar
A1 Pérez Ferré, Natalia
A1 Sánchez Pernaute, Andrés
A1 Torres García, Antonio José
A1 Calle Pascual, Alfonso Luis
AB Purpose Weight regain (WR) compromises the effectiveness of bariatric surgery. The objective of this study was to determine differences in long-term WR prevalence using different definitions and analyze possible preoperative predictors involved.Methods Single-center retrospective cohort study including 445 adults who underwent 3 modalities of bariatric surgery between 2009 and 2014. Exposure: age, gender, ethnicity, body mass index (BMI), type 2 diabetes (T2D), hypertension (HTN), and type of surgery. Main outcomes: WR at year 6 assessed by 4 definitions and 6 multivariate models based on common thresholds.Results Our cohort (71.1% female) had a mean age of 44.78 +/- 11.94 years, and mean presurgery BMI of 44.94 +/- 6.88 kg/m(2), with a median follow-up of 6 years (IQR=5-8). The prevalences of T2D and HTN were 36.0% and 46.7% respectively. WR rates over thresholds ranged from 25.4 to 68.1%, with significant differences between groups in theWRmeasured as the percentage of maximum weight loss (MWL) and the increase in excess weight loss (EWL). Presurgery BMI was a significant predictor in 3 models; restrictive techniques were associated with WR in all the models except for those consideringWR over 10 kg and WR over 15% from nadir as dependent variables.Conclusions In this long-term study, WR defined as percentage of MWL and increase in EWL from nadir had the greatest significance in logistic regression models with preoperative BMI and type of surgery as independent variables. These findings could serve to establish a standardized outcome reporting WR in other longitudinal studies.
PB Springer
SN 0960-8923
YR 2021
FD 2021
LK https://hdl.handle.net/20.500.14352/116800
UL https://hdl.handle.net/20.500.14352/116800
LA eng
NO Torrego-Ellacuría M, Barabash A, Larrad-Sainz A, Hernández-Nuñez GM, Matía- Martín P, Pérez-Ferre N, Marcuello C, Sánchez-Pernaute A, Torres AJ, Calle- Pascual AL, Rubio MA. Weight Regain Outcomes After Bariatric Surgery in the Long-term Follow-up: Role of Preoperative Factors. Obes Surg. 2021 Sep;31(9):3947-3955. doi: 10.1007/s11695-021-05497-5. Epub 2021 Jun 19. PMID: 34146246.
NO Fundación Mutua Madrileña
NO Fundación Estudios Metabólicos
DS Docta Complutense
RD 6 abr 2025