RT Journal Article
T1 Immune Reconstitution After In Utero Bone Marrow Transplantation in a Fetus With Severe Combined Immunodeficiency With Natural Killer Cells
A1 Gil, Juana
A1 Bartolomé Vílchez, Javier
A1 Gurbindo Gutiérrez, María Dolores
A1 Cela De Julián, María Elena
A1 Fernández-Cruz Pérez, Eduardo
A1 Ugazio, Alberto Giovanni
AB BONE MARROW TRANSPLANTATION (BMT) is the elective therapy for severe combined immune deficiencies (SCID). In utero transplant (IUT) of CD341cells from paternal bone marrow (BM) has recently allowed immunologic reconstitution in two fetuses affected with SCID without natural killer (NK) cells.1,2 We report here the first IUT of haploidentical, paternal BM–derived hematopoietic progenitor cells in a male fetus with T2B1NK1 SCID.
PB Elsevier Science
SN 0041-1345
YR 1999
FD 1999-09-03
LK https://hdl.handle.net/20.500.14352/117273
UL https://hdl.handle.net/20.500.14352/117273
LA eng
NO Gil J, Porta F, Bartolomé J, Lafranchi A, Verardi R, Notarangelo LD, Carlo-Stella C, Rodríguez R, Rodríguez JJ, Gurbindo D, Cela E, Zucca A, Fernández-Cruz E, Ugazio AG. Immune reconstitution after in utero bone marrow transplantation in a fetus with severe combined immunodeficiency with natural killer cells. Transplant Proc. 1999 Sep;31(6):2581. doi: 10.1016/s0041-1345(99)00510-2. PMID: 10500727.
DS Docta Complutense
RD 6 abr 2025