RT Journal Article T1 T lymphocyte receptor deficiencies A1 Kappes, Dietmar J A1 Alarcón, Balbino A1 Regueiro González-Barros, José Ramón AB Signalling through the TCR is mediated by the cytoplasmic tails of the CD3 complex. Deficiencies in the expression of different CD3 components have lead to dramatic, yet dissimilar, effects on T-cell development and to selective deficits in peripheral T-cell subsets. Recent studies of human patients and animal models with CD3 deficiencies are providing insights into the redundant and unique roles of these molecules PB Elsevier SN 0952-7915 YR 1995 FD 1995-08 LK https://hdl.handle.net/20.500.14352/107434 UL https://hdl.handle.net/20.500.14352/107434 LA eng NO Kappes DJ, Alarcón B, Regueiro JR. T lymphocyte receptor deficiencies. Curr Opin Immunol. 1995 Aug;7(4):441-7. doi: 10.1016/0952-7915(95)80086-7. DS Docta Complutense RD 5 abr 2025