RT Journal Article
T1 Highly diastereoselective Staudinger reaction on 5,6-dihydropyrazin-2-(1H)-ones. Synthesis of enantiopure fused oxopiperazino-β-lactams
A1 Viso Beronda, Alma
A1 Fernández de la Pradilla Sainz de Aja, Roberto
A1 Flores Aguilar-Amat, Aída
AB The highly diastereoselective synthesis of fused oxopiperazino-β-lactams 2 by Staudinger reaction between functionalized ketenes and 5,6-dihydropyrazin-2(1H)-ones 1 has been carried out. Further cleavage of the β-lactam ring produced 2-oxopiperazine-3-acetic acid derivatives 7 with no epimerization and in good yields.
PB Elsevier
YR 2006
FD 2006-12-11
LK https://hdl.handle.net/20.500.14352/99180
UL https://hdl.handle.net/20.500.14352/99180
LA eng
NO Viso, Alma, et al. «Highly Diastereoselective Staudinger Reaction on 5,6-Dihydropyrazin-2-(1H)-Ones. Synthesis of Enantiopure Fused Oxopiperazino-β-Lactams». Tetrahedron Letters, vol. 47, n.o 50, diciembre de 2006, pp. 8911-15. DOI.org (Crossref), https://doi.org/10.1016/j.tetlet.2006.10.044.
NO Dirección General de Ingresos
DS Docta Complutense
RD 8 abr 2025