RT Journal Article
T1 New Short Strategy for the Synthesis of the Dibenz[b,f]oxepin Scaffold
A1 Moreno, David
A1 Giorgi, Giorgio
A1 Salas, Cristian
A1 Tapia, Ricardo
AB In this report a short and efficient synthesis of the dibenz[b,f]oxepin framework through intramolecular SNAr and McMurry reactions is described. The diaryl ethers required for the McMurry reaction have been obtained in good yields under microwave-assisted conditions of the reaction of salicylaldehydes with fluorobenzaldehydes without catalysts. Application of an intramolecular McMurry reaction to the synthesized diarylethers using TiCl4/Zn in THF gave the target dibenzo[b,f]oxepin system in 53%–55% yields.
PB MDPI
SN 1420-3049
YR 2013
FD 2013-11-26
LK https://hdl.handle.net/20.500.14352/34392
UL https://hdl.handle.net/20.500.14352/34392
LA eng
NO FONDECYT
NO Millenium Nucleus CILIS
NO CONICYT
DS Docta Complutense
RD 8 abr 2025