RT Journal Article
T1 Surgical management of hereditary colorectal cancer: surgery based on molecular analysis and family history
A1 Perea García, José
A1 Marín Gabriel, José Carlos
A1 Díaz Tasende, José Benjamín
A1 Hidalgo, M.
AB The importance of colorectal cancer (CRC) is increasing. A proportion show a hereditary component, as in Lynch syndrome and Familial Adenomatous Polyposis, and a recently defined entity as well, namely, Familial Colorectal Cancer type X. The high probability to develop CRC in these groups may, at the time of recognition, change surgical management, including its timing or even the surgical technique. In some cases prophylactic surgery can play an important role. The possibility of using tools that allow recognition of the aforementioned syndromes, including microsatellite instability, immunohistochemistry for DNA mismatch repair system proteins, and especially their mutations, is on the basis of therapeutic strategies that differ from those employed in sporadic CRC cases
PB Sociedad Española de Patología Digestiva
SN 1130-0108
YR 2009
FD 2009
LK https://hdl.handle.net/20.500.14352/130719
UL https://hdl.handle.net/20.500.14352/130719
LA eng
NO Perea J, Justo I, Alvaro E, Lomas M, Tasende JD, Marín JC, Franco A, Colina F, Rodríguez Y, Martínez J, Robles L, Urioste M, Hidalgo M. Surgical management of hereditary colorectal cancer: surgery based on molecular analysis and family history. Rev Esp Enferm Dig. 2009 Aug;101(8):536-40. doi: 10.4321/s1130-01082009000800003
DS Docta Complutense
RD 7 abr 2026