TY - JOUR AU - Marco, Isabel AU - Valhondo Falcón, Margarita AU - Martín-Fontecha Corrales, María Del Mar AU - Vázquez Villa, María Del Henar AU - Del Rio, Joaquin AU - Planas, Anna AU - Sagredo Ezquioga, Onintza AU - Ramos Atance, José Antonio AU - Torrecillas, Iván R. AU - Pardo, Leonardo AU - Frechilla, Diana AU - Benhamú Salama, Bellinda AU - López Rodríguez, María Luz PY - 2011 DO - 10.1021/jm2007886 SN - 0022-2623 UR - https://hdl.handle.net/20.500.14352/113955 T2 - Journal of Medicinal Chemistry AB - We report the synthesis of new compounds 4–35 based on structural modifications of different moieties of previously described lead UCM-2550. The new nonpiperazine derivatives, representing second-generation agonists, were assessed for binding... LA - eng M2 - 7986 PB - ACS Publications KW - Serotonin 5-HT1A receptor KW - Agonists KW - Structure–affinity relationships KW - Neuroprotection KW - Ischemic cell damage TI - New serotonin 5-HT1A receptor agonists with neuroprotective effect against ischemic cell damage TY - journal article VL - 54 ER -