TY  - JOUR
AU  - Cordani, Marco
AU  - Garufi, Alessia
AU  - Benedetti, Rossella
AU  - Tafani, Marco
AU  - Aventaggiato, Michele
AU  - D’Orazi, Gabriella
AU  - Cirone, Mara
PY  - 2024
DO  - 10.3390/biom14060649
SN  - 2218-273X
UR  - https://hdl.handle.net/20.500.14352/118713
T2  - Biomolecules
AB  - The p53 protein is the master regulator of cellular integrity, primarily due to its tumor-suppressing functions. Approximately half of all human cancers carry mutations in the TP53 gene, which not only abrogate the tumor-suppressive functions but also...
LA  - eng
PB  - MDP
KW  - Mutant p53
KW  - Cancer secretome
KW  - Extracellular vesicles
KW  - Tumor microenvironment
KW  - MDM2
KW  - Proteasome
KW  - Ubiquitination
KW  - Chaperone-mediated autophagy (CMA)
KW  - Heat shock proteins (HSP)
TI  - Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions
TY  - journal article
VL  - 14
ER  -