RT Journal Article
T1 Neurological manifestations of COVID-19 in patients: from path physiology to therapy
A1 Merino Martín, José Joaquín
A1 Macho González, Adrián
A1 Benedí González, Juana María
A1 González Gómez, María Paloma
AB AbstractCoronavirus is a family of ARN positive single-stranded belonging to the family of Coronaviridae. There are several families of coronavirus that transmit more or less serious diseases. However, the so-called coronavirus-19 (SARS-CoV2) is the one that is currently causing most of the problems; in fact, biological dysfunctions that this virus causes provoke damage in various organs, from the lung to the heart, the kidney, the circulatory system, and even the brain. The neurological manifestations caused by viral infection, as well as the hypercoagulopathy and systemic inflammation, have been reported in several studies. In this review, we update the neurological mechanisms by which coronavirus-19 causes neurological manifestation in patients such as encephalomyelitis, Guillain-Barré syndrome, lacunars infarcts, neuropsychiatry disorders such as anxiety and depression, and vascular alterations. This review explains (a) the possible pathways by which coronavirus-19 can induce the different neurological manifestations, (b) the strategies used by the virus to cross the barrier system, (c) how the immune system responds to the infection, and (d) the treatment than can be administered to the COVID-19 patients.
PB Springer Nature
SN 1590-1874
YR 2021
FD 2021
LK https://hdl.handle.net/20.500.14352/115640
UL https://hdl.handle.net/20.500.14352/115640
LA eng
NO Merino JJ, Macho-González A, Benedi J, González MP. Neurological manifestations of COVID-19 in patients: from path physiology to therapy. Neurol Sci. 2021 Dec;42(12):4867-4879. doi: 10.1007/s10072-021-05505-7. Epub 2021 Aug 21. PMID: 34417704; PMCID: PMC8379040.
DS Docta Complutense
RD 6 abr 2025