RT Journal Article T1 Management of Intracranial Hemorrhage During Pulsatile Long-Term Biventricular Support: When Necessity Is the Mother of Invention. A1 Martínez Solano, Jorge A1 Ortiz Bautista, Carlos A1 Zatarain Nicolás, Eduardo A1 Sousa Casasnovas, Iago A1 Pedraz Prieto, Álvaro A1 Barrio Gutiérrez, Jose María A1 Pascual Izquierdo, María Cristina A1 Fernández-Avilés Díaz, Francisco Jesús AB Despite improvements in device design and hemocompatibility, intracranial hemorrhage and stroke remain the most feared and devastating complications in patients under mechanical circulatory support. We present the case of a 48-year-old man with advanced heart failure (INTERMACS 3) and severe biventricular dysfunction who underwent biventricular pulsatile paracorporeal device implantation (Berlin Heart Excor®) as a bridge to candidacy. While on the heart transplantation waiting list, the patient experienced an intracranial hemorrhage, which was successfully managed by switching to a less thrombogenic biventricular assist device (Levitronix Centrimag®) using the Excor® cannulae, thus enabling temporary withdrawal of antithrombotic therapy. Heart transplant was performed successfully with no significant complications. PB Lippincott, Williams & Wilkins YR 2021 FD 2021-10-01 LK https://hdl.handle.net/20.500.14352/117562 UL https://hdl.handle.net/20.500.14352/117562 LA eng NO Martínez-Solano J, Ortiz-Bautista C, Zatarain-Nicolás E, Sousa-Casasnovas I, Pedraz-Prieto Á, Barrio-Gutiérrez JM, Pascual-Izquierdo C, Fernández-Avilés F. Management of Intracranial Hemorrhage During Pulsatile Long-Term Biventricular Support: When Necessity Is the Mother of Invention. ASAIO J. 2021 Oct 1;67(10):e172-e175. PMID 33528165. DS Docta Complutense RD 10 abr 2025