RT Journal Article T1 Production of Fumaric Acid by Rhizopus arrhizus NRRL 1526:A Simple Production Medium and the Kinetic Modelling ofthe Bioprocess A1 Martin-Dominguez, Victor A1 Aleman Cabrera, Paula I A1 Eidt, Laslo A1 Pruesse, Ulf A1 Kuenz, Anja A1 Ladero Galán, Miguel A1 Santos Mazorra, Victoria Eugenia AB Fumaric acid is a promising monomer to obtain biomass-based polyesters and polyamides, and it is mainly produced by fungi of the Rhizopus genus in medium to high titters. The use of glucose, a main component of starchy and cellulosic food waste, as carbon source, together with a low-nitrogen source concentration, is a promising route to reduce process costs. In this work, the effects of nitrogen and carbonate sources on Rhizopus arrhizus NRRL 1526 morphology and fumaric acid productivity were analysed, simplifying the traditional production broth composition. Moreover, a non-structured, non-segregated kinetic model was proposed and fitted to concentration data of all relevant components obtained in batches performed in triplicate with the selected production broth at 34 °C and 200 rpm in an orbital shaker. PB MDPI SN 2311-5637 YR 2022 FD 2022 LK https://hdl.handle.net/20.500.14352/72322 UL https://hdl.handle.net/20.500.14352/72322 LA eng NO Ministerio de Ciencia, Innovación NO German Bundestag, via the Agency of Renewable Resources DS Docta Complutense RD 5 may 2024