RT Journal Article
T1 A novel group of avian astroviruses from Neotropical passerine birds broaden the diversity and hostrange of Astroviridae
A1 Fernández-Correa, Izaskun
A1 Truchado Martín, Daniel Alejandro
A1 Gómez-Lucía Duato, María Esperanza
A1 Doménech, Ana
A1 Pérez Tris, Javier
A1 Schmidt-Chanasit, Jonas
A1 Cadar, Daniel
A1 Benítez Rico, Laura
AB Metagenomics is helping to expand the known diversity of viruses, especially of those with poorly studied hosts in remote areas. The Neotropical region harbors a considerable diversity of avian species that may play a role as both host and short-distance vectors of unknown viruses. Viral metagenomics of cloacal swabs from 50 Neotropical birds collected in French Guiana revealed the presence of four complete astrovirus genomes. They constitute an early diverging novel monophyletic clade within the Avastrovirus phylogeny, representing a putative new astrovirus species (provisionally designated as Avastrovirus 5) according to the International Committee on Taxonomy of Viruses (ICTV) classifcation criteria. Their genomic organization shares some characteristics with Avastrovirus but also with Mamastrovirus. The pan-astrovirus RT-PCR analysis of the cloacal samples of 406 wild Neotropical birds showed a community-level prevalence of 4.9% (5.1% in passerines, the highest described so far in this order of birds). By screening birds of a remote region, we expanded the known host range of astroviruses to the avian families Cardinalidae, Conopophagidae, Furnariidae, Thamnophilidae, Turdidae and Tyrannidae. Our results provide important frst insights into the unexplored viral communities, the ecology, epidemiology and features of host-pathogen interactions that shape the evolution of avastroviruses in a remote Neotropical rainforest.
PB Nature Research
SN ESSN: 2045-2322
YR 2019
FD 2019-07-02
LK https://hdl.handle.net/20.500.14352/13740
UL https://hdl.handle.net/20.500.14352/13740
LA eng
NO Ministerio de Economía y Competitividad (MINECO)/FEDER
NO Agence Nationale de la Recherche (ANR)
NO Universidad Complutense de Madrid
DS Docta Complutense
RD 30 abr 2024