RT Journal Article T1 A High Adherence to Six Food Targets of the Mediterranean Diet in the Late First Trimester is Associated with a Reduction in the Risk of Materno-Foetal Outcomes: The St. Carlos Gestational Diabetes Mellitus Prevention Study A1 Assaf Balut, Carla A1 García De La Torre, Nuria A1 Fuentes, Manuel A1 Durán Rodríguez-Hervada, Alejandra A1 Bordiú, Elena A1 Valle, Laura Del A1 Valerio, Johanna A1 Jiménez, Inés A1 Herraiz Martínez, Miguel Ángel A1 Izquierdo Méndez, Nuria A1 Torrejón, María A1 De Miguel Novoa, María De La Paz A1 Barabash Bustelo, Ana A1 Cuesta, Martín A1 Rubio Herrera, Miguel Ángel A1 Calle Pascual, Alfonso Luis AB A prenatal diet affects materno-foetal outcomes. This is a post hoc analysis of the St. Carlos gestational diabetes mellitus (GDM) Prevention Study. It aims to evaluate the effect of a late first-trimester (>12 gestational weeks) degree of adherence to a MedDiet pattern—based on six food targets—on a composite of materno-foetal outcomes (CMFCs). The CMFCs were defined as having emergency C-section, perineal trauma, pregnancy-induced hypertension and preeclampsia, prematurity, large-for-gestational-age, and/or small-for-gestational-age. A total of 874 women were stratified into three groups according to late first-trimester compliance with six food targets: >12 servings/week of vegetables, >12 servings/week of fruits, <2 servings/week of juice, >3 servings/week of nuts, >6 days/week consumption of extra virgin olive oil (EVOO), and ≥40 mL/day of EVOO. High adherence was defined as complying with 5–6 targets; moderate adherence 2–4 targets; low adherence 0–1 targets. There was a linear association between high, moderate, and low adherence, and a lower risk of GDM, CMFCs, urinary tract infections (UTI), prematurity, and small-for-gestational-age (SGA) newborns (all p < 0.05). The odds ratios (95% CI) for GDM and CMFCs in women with a high adherence were 0.35((0.18–0.67), p = 0.002) and 0.23((0.11–0.48), p < 0.001), respectively. Late first-trimester high adherence to the predefined six food targets is associated with a reduction in the risk of GDM, CMFCs, UTI, prematurity, and SGA new-borns. PB MDPI SN 2072-6643 YR 2018 FD 2018-12-31 LK https://hdl.handle.net/20.500.14352/12581 UL https://hdl.handle.net/20.500.14352/12581 LA eng NO Assaf Balut, C., García De La Torre, N., Fuentes, M. et al. «A High Adherence to Six Food Targets of the Mediterranean Diet in the Late First Trimester Is Associated with a Reduction in the Risk of Materno-Foetal Outcomes: The St. Carlos Gestational Diabetes Mellitus Prevention Study». Nutrients, vol. 11, n.o 1, diciembre de 2018, p. 66. DOI.org (Crossref), https://doi.org/10.3390/nu11010066. NO Instituto de Salud Carlos III/Fondo Europeo de Desarrollo Regional NO Comunidad de Madrid DS Docta Complutense RD 18 abr 2025