TY - JOUR AU - Gil Calle, Juana Nelly AU - Busto, Elena M AU - Garcillán Goyoaga, Beatriz de AU - Chean, Carmen AU - García Rodríguez, María Cruz AU - Díaz Alderete, Andrea AU - Navarro, Joaquín AU - Reiné Gutiérrez, Jesús AU - Mencía, Ángeles AU - Gurbindo, Dolores AU - Beléndez, Cristina AU - Gordillo, Isabel AU - Duchniewicz, Marlena AU - Höhne, Kerstin AU - García Sánchez, Félix AU - Fernández Cruz, Eduardo AU - López Granados, Eduardo AU - Schamel, Wolfgang W.A. AU - Moreno Pelayo, Miguel A AU - Recio Hoyas, María José AU - Regueiro González-Barros, José Ramón PY - 2011 DO - 10.1172/JCI44254 SN - 0021-9738; 1558-8238 UR - https://hdl.handle.net/20.500.14352/43344 T2 - The Journal of Clinical Investigation AB - T cells recognize antigens via their cell surface TCR and are classified as either αβ or γδ depending on the variable chains in their TCR, α and β or γ and δ, respectively. Both αβ and γδ TCRs also contain several invariant chains, including CD3δ,... LA - eng M2 - 3872 PB - American Society for Clinical Investigation TI - A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ−Tγδ+B+NK+ human SCID TY - journal article VL - 121 ER -