TY  - JOUR
AU  - González Cofrade, Laura
AU  - J. P. Green
AU  - Heras Polo, Beatriz De Las
AU  - Terencio, Carmen
AU  - Hortelano, Sonsoles
AU  - Brough, David
AU  - Estévez-Braun, Ana
AU  - Ferrándiz, Laría Luisa
AU  - Cuadrado Berrocal, Irene
PY  - 2025
DO  - 10.1016/j.bcp.2025.117114
UR  - https://hdl.handle.net/20.500.14352/128921
T2  - Biochemical Pharmacology
AB  - Natural products constitute an important resource for drug discovery with hispanolone derivatives recognized as bioactive diterpenes due to their broad therapeutic potential. Dehydroisohispanolone (DIH) is an anti-inflammatory labdane diterpene, that...
LA  - eng
KW  - Dehydroisohispanolone
KW  - NLRP3 inflammasome
KW  - IL-1β
KW  - ASC
KW  - Macrophages
KW  - Gouty arthritis
TI  - Dehydroisohispanolone alleviates NLRP3-driven inflammation in gout arthritis
TY  - journal article
VL  - 240
ER  -