TY  - JOUR
AU  - García Esteban, María Teresa
AU  - Carreño, David
AU  - Tirado Vélez, José Manuel
AU  - Ferrándiz, María José
AU  - Rodrigues, Liliana
AU  - Gracia, Begoña
AU  - Amblar, Mónica
AU  - Ainsa, José A.
AU  - Gonzalez de la Campa, Adela
PY  - 2018
DO  - 10.3389/fmicb.2018.01659
SN  - 1664-302X
UR  - https://hdl.handle.net/20.500.14352/112403
T2  - Frontiers in Microbiology
AB  - The spread of multidrug-resistant isolates of Mycobacterium tuberculosis requires the discovery of new drugs directed to new targets. In this study, we investigated the activity of two boldine-derived alkaloids, seconeolitsine (SCN) and...
LA  - eng
M2  - 1
PB  - Frontiers Media
KW  - Mycobacterium tuberculosis
KW  - DNA topoisomerase I inhibitor
KW  - DNA supercoiling
KW  - N-methylseconeolitsine
KW  - Seconeolitsine
KW  - Antituberculosis activity
KW  - Drug discovery
TI  - Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of Mycobacterium tuberculosis
TY  - journal article
VL  - 9
ER  -