RT Journal Article
T1 Decontamination of biofilm-contaminated implant surfaces: An in vitro evaluation
A1 Ichioka, Yuki
A1 Virto Ruiz, Leire
A1 Nuevo, Paula
A1 Gamonal, Juan Daniel
A1 Derks, Jan
A1 Larsson, Lena
A1 Sanz, Mariano
A1 Berglundh, Tord
AB Objectives: The aim of the present study was to evaluate the cleaning efficacy of two mechanical and two chemical protocols in the decontamination of implant surfaces. Methods: In total, 123 commercially available implants were mounted in plastic models mimicking peri-implant circumferential intra-bony defects. A multispecies biofilm was grown on implant surfaces. Mechanical (air-polishing (AP), rotating titanium brush (TiB)) and chemical decontamination (alkaline electrolyzed water, N-acetyl-L-cysteine) protocols were used. Cleaning efficacy in terms of residual biofilm area, chemical surface properties, and bacterial counts were analyzed by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and quantitative polymerase chain reaction. Results: Surface decontamination protocols including use of an AP device or a rotating TiB were superior in terms of biofilm removal and in reducing atomic% of Carbon on implant surfaces when compared to methods restricted to wiping with gauze. The use of chemical agents as adjuncts to the mechanical cleaning protocols provided no relevant overall benefit over saline. No treatment modality, however, resulted in complete biofilm removal. Conclusion: Air-polishing and rotating TiB were more effective implant surface decontamination protocols than wiping with gauzes. Use of chemical agents did not improve cleaning efficacy
PB John Wiley & Sons Ltd
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/92487
UL https://hdl.handle.net/20.500.14352/92487
LA eng
NO : Ichioka, Y., Virto, L., Nuevo, P., Gamonal, J. D., Derks, J., Larsson, L., Sanz, M., & Berglundh, T. (2023). Decontamination of biofilm-contaminated implant surfaces: An in vitro evaluation. Clinical Oral Implants Research, 00, 1–15.
NO TUA research funding
NO University of Gothenburg and the National Microscopy Infrastructure
DS Docta Complutense
RD 29 abr 2025