TY - JOUR AU - Roscales García, Silvia AU - Bechmann, Nicole AU - Holger Weiss, Daniel AU - Köckerling, Martin AU - Pietzsch, Jens AU - Kniess, Torsten PY - 2018 DO - 10.1039/c7md00575j UR - https://hdl.handle.net/20.500.14352/126384 T2 - MedChemComm AB - Novel valdecoxib-based cyclooxygenase-2 inhibitors were synthesized in one step via 1,3-dipolar cycloaddition of nitrile oxides with a series of eleven aryl alkynes, six of them described for the first time. Application of RuIJII)-catalysis leads... LA - eng M2 - 534 TI - Novel valdecoxib derivatives by rutheniumIJII) promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes– synthesis and COX-2 inhibition activity TY - journal article VL - 9 ER -