RT Journal Article
T1 Agreement between Five Experts and the Laguna ONhE Automatic Colourimetric Application Interpreting the Glaucomatous Aspect of the Optic Nerve
A1 Méndez Hernández, Carmen Dora
A1 Gutiérrez Díaz, María Esperanza
A1 Pazos, Marta
A1 Giménez Gómez, Rafael
A1 Pinazo Durán, María Dolores
AB Background: Optic nerve head (ONH) interpretation is a glaucoma screening method which may be influenced by criteria variability. Laguna ONhE software is a low-cost and non-invasive method of ONH analysis. Methods: We analysed the results of the Laguna ONhE application, interpreting 552 ONH images from the ACRIMA database, publicly available on the Internet, and compared them with the opinion of five experts. Diagnostic agreement was investigated using Cohen’s kappa (κ) with 95% confidence. Results: The kappa concordance index obtained with Laguna ONhE and the majority of the experts’ criterion (0.77) was significantly higher compared to that obtained with ACRIMA and the majority of the experts’ criterion (0.61). In 44.7% of the cases there was absolute agreement among the 5 experts and the Laguna ONhE program. Removing borderline cases from the analysis yielded increased diagnostic agreement (0.81). The area under the receiver operating characteristic (AUROC) of the Laguna ONhE program (0.953, p < 0.001) was not significantly different than AUROC of the majority of the experts’ criterion (0.925, p < 0.001), p = 0.052. Individually obtained expert’s AUROCs were significantly lower (0.636 to 0.913; p < 0.01). Conclusions: Laguna ONhE’s agreement with the experts is high, particularly where the diagnosis may be more obvious by the appearance of the ONH.
PB MDPI
YR 2023
FD 2023-08-24
LK https://hdl.handle.net/20.500.14352/119527
UL https://hdl.handle.net/20.500.14352/119527
LA eng
NO Mendez-Hernandez, C., Gutierrez-Diaz, E., Pazos, M., Gimenez-Gomez, R., & Pinazo-Duran, M. D. (2023). Agreement between Five Experts and the Laguna ONhE Automatic Colourimetric Application Interpreting the Glaucomatous Aspect of the Optic Nerve. Journal of Clinical Medicine, 12(17), 5485. https://doi.org/10.3390/jcm12175485
DS Docta Complutense
RD 30 dic 2025